Episode 173 Childhood Vaccine Schedule 2: Who’s making the call?

After last week’s episode, we all know about each of the diseases that we’re protected against thanks to our childhood vaccine schedule here in the US. And after this week’s episode, we’ll understand more about the schedule itself – why it might look different from other schedules around the world, how it gets made, and who makes the recommendations. We’ll also review some of the current outbreaks of vaccine-preventable diseases before leaving you with some of our thoughts on how to talk about vaccines and vaccine hesitancy.

History of ACIPWHO Schedules and Epidemiology
Walton, L. Reed, Walter A. Orenstein, and Larry K. Pickering. “The history of the United States Advisory Committee on Immunization Practices (ACIP).” Vaccine 33.3 (2015): 405-414.Hotez, P., 2019. America and Europe’s new normal: the return of vaccine-preventable diseases. Pediatric Research, 85(7), pp.912-914.
Offit, Paul, and Charlotte Moser. “The Vaccine Schedule.” Vaccines and Your Family. Columbia University Press, 2024. 304-318.WHO Table 1: Summary of WHO Position Papers – Recommendations for Routine Immunization https://www.who.int/publications/m/item/table1-summary-of-who-position-papers-recommendations-for-routine-immunization
https://www.cdc.gov/acip/membership/index.htmlCDC Child and Adolescent Immunization Schedule by Age. https://www.cdc.gov/vaccines/hcp/imz-schedules/child-adolescent-age.html
https://www.cdc.gov/vaccines-children/schedules/who-sets.htmlCDC Measles Cases and Outbreaks https://www.cdc.gov/measles/data-research/index.html (updated as of Feb 28, 2025 at the time of recording)
https://www.science.org/content/article/how-much-power-do-trump-and-kennedy-have-reshape-health-agenciesCenters for Disease Control and Prevention. 2024 Provisional Pertussis Surveillance Report. Atlanta, GA: CDC. Jan 2025.
https://www.cdc.gov/acip/meetings/index.htmlMercader-Barceló, J., Otu, A., Townley, T.A., Adepoju, P., Walley, J., Okoibhole, L.O. and Ebenso, B., 2022. Rare recurrences of poliomyelitis in non-endemic countries after eradication: a call for global action. The Lancet Microbe, 3(12), pp.e891-e892.
https://www.cdc.gov/mmwr/preview/mmwrhtml/00041753.htmNelson, N.P., 2020. Prevention of hepatitis A virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices, 2020. MMWR. Recommendations and Reports, 69.
https://www.cdc.gov/mmwr/preview/mmWrhtml/rr5515a1.htmWHO Global Immunization Dashboard. https://immunizationdata.who.int/
WHO Ten Threats to Global Health 2019. https://www.who.int/news-room/spotlight/ten-threats-to-global-health-in-2019
Vaccine hesitancy
Bussink-Voorend, D., Hautvast, J.L., Vandeberg, L., Visser, O. and Hulscher, M.E., 2022. A systematic literature review to clarify the concept of vaccine hesitancy. Nature Human Behaviour, 6(12), pp.1634-1648.
Williams, S.E., 2014. What are the factors that contribute to parental vaccine-hesitancy and what can we do about it?. Human vaccines & immunotherapeutics, 10(9), pp.2584-2596.
McClure, C.C., Cataldi, J.R. and O’Leary, S.T., 2017. Vaccine hesitancy: where we are and where we are going. Clinical therapeutics, 39(8), pp.1550-1562.
Omer, S.B., Salmon, D.A., Orenstein, W.A., Dehart, M.P. and Halsey, N., 2009. Vaccine refusal, mandatory immunization, and the risks of vaccine-preventable diseases. New England Journal of Medicine, 360(19), pp.1981-1988.
Ruggeri, K., Vanderslott, S., Yamada, Y., Argyris, Y.A., Većkalov, B., Boggio, P.S., Fallah, M.P., Stock, F. and Hertwig, R., 2024. Behavioural interventions to reduce vaccine hesitancy driven by misinformation on social media. Bmj, 384.
Greenberg, J., Dubé, E. and Driedger, M., 2017. Vaccine hesitancy: in search of the risk communication comfort zone. PLoS currents, 9, pp.ecurrents-outbreaks.

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