Hemorrhagic virus? Check. Deadly disease? Check. Mosquito-borne? Check. Affected by animal movement, human activity, and environmental change? Check. Rift Valley Fever has all the markings of a classic TPWKY episode. This week, we’re doing a deep dive on this deadly virus, taking a One Health approach to explore the intricate relationships between animals, humans, and the environment to understand how this virus moves across the landscape. We trace the various paths this virus takes: through the organisms it infects, across the globe as it spreads, and over time as it appears to be evolving to be deadlier. Tune in to learn more about Rift Valley fever and what we might see with this pathogen in the years to come.
| History | Biology |
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| Chemison, Alizée, et al. “Ability of a dynamical climate sensitive disease model to reproduce historical Rift Valley Fever outbreaks over Africa.” Scientific Reports 14.1 (2024): 3904. | Kwaśnik, M., Rożek, W. and Rola, J., 2021. Rift Valley fever–a growing threat to humans and animals. Journal of veterinary research, 65(1), pp.7-14. |
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| Davies, F. Glyn. “The historical and recent impact of Rift Valley fever in Africa.” The American journal of tropical medicine and hygiene 83.2 Suppl (2010): 73. | Connors, K.A. and Hartman, A.L., 2022. Advances in understanding neuropathogenesis of rift valley fever virus. Annual review of virology, 9(1), pp.437-450. |
| British east Africa. (1913). Annual Report of the Department Of Agriculture, Nairobi : British East Africa, For 1912-1913. https://kalroerepository.kalro.org/handle/0/7556 | Hartman, A., 2017. Rift valley fever. Clinics in laboratory medicine, 37(2), pp.285-301. |
| British east Africa. (1914). Annual Report of the Department Of Agriculture, Nairobi : British East Africa, For 1913-1914. https://kalroerepository.kalro.org/items/a27a5210-d5a6-496f-834f-7e0aeadc71ca/full | Petrova, V., Kristiansen, P., Norheim, G. and Yimer, S.A., 2020. Rift valley fever: diagnostic challenges and investment needs for vaccine development. BMJ Global Health, 5(8), p.e002694. |
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| Findlay, GM5. “Rift Valley fever or enzootic hepatitis.” Transactions of the Royal Society of Tropical Medicine and Hygiene 25.4 (1932): 229-IN11. | Ikegami, T. and Makino, S., 2011. The pathogenesis of Rift Valley fever. Viruses, 3(5), pp.493-519. |
| McMillen, Cynthia M., and Amy L. Hartman. “Rift Valley fever in animals and humans: Current perspectives.” Antiviral research 156 (2018): 29-37. | Wichgers Schreur, P.J., Vloet, R.P., Kant, J., van Keulen, L., Gonzales, J.L., Visser, T.M., Koenraadt, C.J., Vogels, C.B. and Kortekaas, J., 2021. Reproducing the Rift Valley fever virus mosquito-lamb-mosquito transmission cycle. Scientific Reports, 11(1), p.1477. |
| Mellor, P. S., and C. J. Leake. “Climatic and geographic influences on arboviral infections and vectors.” Revue Scientifique et Technique-Office International des Epizooties 19.1 (2000): 41-60. | Nanyingi, M.O., Munyua, P., Kiama, S.G., Muchemi, G.M., Thumbi, S.M., Bitek, A.O., Bett, B., Muriithi, R.M. and Njenga, M.K., 2015. A systematic review of Rift Valley Fever epidemiology 1931–2014. Infection ecology & epidemiology, 5(1), p.28024. |
| Munyua, Peninah M., et al. “Predictive factors and risk mapping for Rift Valley fever epidemics in Kenya.” PLoS One 11.1 (2016): e0144570. | Kitandwe, P.K., McKay, P.F., Kaleebu, P. and Shattock, R.J., 2022. An overview of Rift Valley fever vaccine development strategies. Vaccines, 10(11), p.1794. |
| Murithi, R. M., et al. “Rift Valley fever in Kenya: history of epizootics and identification of vulnerable districts.” Epidemiology & Infection 139.3 (2011): 372-380. | Petrova, V., Kristiansen, P., Norheim, G. and Yimer, S.A., 2020. Rift valley fever: diagnostic challenges and investment needs for vaccine development. BMJ Global Health, 5(8), p.e002694. |
| Pienaar, Nicolaas J., and Peter N. Thompson. “Temporal and spatial history of Rift Valley fever in South Africa: 1950 to 2011.” Onderstepoort Journal of Veterinary Research 80.1 (2013): 1-13. | World Organization for Animal Health. Rift Valley Fever. https://www.woah.org/en/disease/rift-valley-fever/ |
| MMWR/WER, Collective. “Rift Valley fever-East Africa, 1997-98.” Eurosurveillance 2.15 (1998). | World Health Organization. Feb 2018. Rift Valley Fever Factsheet. https://www.who.int/news-room/fact-sheets/detail/rift-valley-fever |
| Schwentker, Francis F., and Thomas M. Rivers. “Rift Valley fever in man: report of a fatal laboratory infection complicated by thrombophlebitis.” The Journal of experimental medicine 59.3 (1934): 305. | World Health Organization, Oct 2022. Disease outbreak news. Rift Valley fever—Mauritania. https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON417 |
| Situma, Silvia, et al. “Widening geographic range of Rift Valley fever disease clusters associated with climate change in East Africa.” BMJ Global Health 9.6 (2024): e014737. | World Health Organization, Feb 2021. Disease outbreak news. Rift Valley fever – Kenya. https://www.who.int/emergencies/disease-outbreak-news/item/2021-DON311 |
| Xue, Ling, et al. “A hierarchical network approach for modeling Rift Valley fever epidemics with applications in North America.” PLoS One 8.5 (2013): e62049. | World Health Organization, Nov 2020. Disease outbreak news. Rift Valley fever – Mauritania. https://www.who.int/emergencies/disease-outbreak-news/item/rift-valley-fever-mauritania |
| Ebogo‐Belobo, J.T., Kenmoe, S., Abanda, N.N., Bowo‐Ngandji, A., Mbaga, D.S., Magoudjou‐Pekam, J.N., Kame‐Ngasse, G.I., Tchatchouang, S., Menkem, E.Z.O., Okobalemba, E.A. and Noura, E.A., 2023. Contemporary epidemiological data of Rift Valley fever virus in humans, mosquitoes and other animal species in Africa: A systematic review and meta‐analysis. Veterinary Medicine and Science, 9(5), pp.2309-2328. |
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