On the night of December 2, 1984, a deadly gas leak at the Union Carbide pesticide plant in Bhopal, India led to what has been described as the world’s worst industrial disaster. In the immediate aftermath of the gas leak, thousands of people died and hundreds of thousands were injured from exposure to the toxic gas methyl isocyanate. But long after the international headlines and news reports dwindled to silence, long after Union Carbide paid a paltry settlement to survivors, long after the disaster faded from much of the world’s memory, the gas leak continues to haunt the residents of Bhopal. In this episode, we trace the path of methyl isocyanate from initial discovery to the night of the disaster and the years that followed. We then explore what about this gas makes it so very deadly before assessing how the contamination still present at the site is causing health problems for residents decades after the gas leak.
| History | Biology |
| Lapierre, Dominique, and Javier Moro. Five past midnight in Bhopal: The epic story of the world’s deadliest industrial disaster. Hachette UK, 2009. | Mehta, P.S., Mehta, A.S., Mehta, S.J. and Makhijani, A.B., 1990. Bhopal tragedy’s health effects: a review of methyl isocyanate toxicity. Jama, 264(21), pp.2781-2787. |
| Broughton, Edward. “The Bhopal disaster and its aftermath: a review.” Environmental Health 4.1 (2005): 1-6. | Varma, R. and Varma, D.R., 2005. The Bhopal disaster of 1984. Bulletin of Science, Technology & Society, 25(1), pp.37-45. |
| Carpenter, C. P., et al. “Insecticide toxicology, mammalian toxicity of 1-naphthyl-N-methylcarbamate (Sevin insecticide).” Journal of Agricultural and Food Chemistry 9.1 (1961): 30-39. | Vijayan, V.K., 2010. Methyl isocyanate (MIC) exposure and its consequences on human health at Bhopal. International journal of environmental studies, 67(5), pp.637-653. |
| Stewart, Nelson E., Raymond E. Millemann, and Wilbur P. Breese. “Acute toxicity of the insecticide Sevin® and its hydrolytic product 1-naphthol to some marine organisms.” Transactions of the American Fisheries Society 96.1 (1967): 25-30. | Bucher, J.R., 1987. Methyl isocyanate: a review of health effects research since Bhopal. Fundamental and applied toxicology, 9(3), pp.367-379. |
| Daya R. Varma & Ian Guest (1993) The Bhopal accident and methyl isocyanate toxicity, Journal of Toxicology and Environmental Health, Part A Current Issues, 40:4, 513-529, DOI: 10.1080/15287399309531816 | |
| Bucher, J.R., 1987. The toxicity of methyl isocyanate: Where do we stand?. Environmental Health Perspectives, 72, pp.197-198. | |
| Mishra, P.K., Samarth, R.M., Pathak, N., Jain, S.K., Banerjee, S. and Maudar, K.K., 2009. Bhopal gas tragedy: review of clinical and experimental findings after 25 years. International journal of occupational medicine and environmental health, 22(3), p.193. | |
| Rancourt, R.C., Rioux, J.S., Veress, L.A., Garlick, R.B., Croutch, C.R., Peters, E., Sosna, W. and White, C.W., 2019. Methyl isocyanate inhalation induces tissue factor-dependent activation of coagulation in rats. Drug and chemical toxicology, 42(3), pp.321-327. | |
| Varma, D., Mulay, S., “Methyl Isocyanate the Bhopal gas” from Handbook of Toxicology of Chemical Warfare Agents (2nd Edition) Chapter 22 Elsevier. Gupta, Ramesh C. eds (2015) | |
| Broughton, E., 2005. The Bhopal disaster and its aftermath: a review. Environmental Health, 4(1), pp.1-6. | |
| Sharma, D.C., 2005. Bhopal: 20 years on. The Lancet, 365(9454), pp.111-112. | |
| Sharma, D.C., 2013. Bhopal study represents “missed opportunity”. The Lancet, 382(9908), p.1870. | |
| Senthilkumar, C.S., Sah, N.K. and Ganesh, N., 2012. Methyl isocyanate and carcinogenesis: bridgeable gaps in scientific knowledge. Asian Pac J Cancer Prev, 13(6), pp.2429-2435. | |
| Sharma, S. “The politics of remembering Bhopal” in Displaced Heritage: responses to disaster, trauma, and loss Ch 10. Eds Converey, I., Corsane, G., Davis, P. 2014 | |
| Sharma, S. 2014 The Bhopal Disaster and its aftermath: conflict over safe water, environment and justice. In Conflicts around domestic water and sanitation in India: cases, issues and prosects eds: Joy, KJ., Paranjape, S., Bhagat, S. 2014. | |
| Halfen, D.T., Ilyushin, V.V. and Ziurys, L.M., 2015. Interstellar detection of methyl isocyanate CH3NCO in Sgr B2 (N): A link from molecular clouds to comets. The Astrophysical Journal Letters, 812(1), p.L5. |
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