Season 2

Episode 15 MRSA: Make Resistance Susceptible Again

We’ve gotten pretty graphic on this podcast before, but this episode takes it to a whole new level. The omnipresent Staphylococcus aureus is a bacterium that wears many faces. Often that face is harmless, but Staph has the power to invade and infect nearly every organ of the body, leaving destruction (and a lot of pus) in its wake. While Staphylococcus aureus has been wreaking havoc on humans since well before the discovery of antibiotics, Methicillin-resistant Staph aureus (MRSA) has risen to terrifying prominence as resistance becomes the new norm. If any disease could make you run out (or stay in) and wash your hands, it’s this one. 

HistoryBiology
Superbug: The Fatal Menace of MRSA by Maryn McKennaA new class of synthetic retinoid antibiotics effective against bacterial persisters” Kim et al 2018
Shinefield, Henry R., and Naomi L. Ruff. “Staphylococcal infections: a historical perspective.” Infectious disease clinics of North America 23.1 (2009): 1-15.Antibacterial Properties of Four Novel Hit Compounds from a Methicillin-Resistant Staphylococcus aureus–Caenorhabditis elegans High-Throughput Screen” Tharmalingam et al 2018
The Rise of Methicillin-Resistant Staphylococcus aureus in U.S.Correctional Populations” Bianca Malcom 2011
Discovery of MRSA active antibiotics using primary sequence from the human microbiome” Chu et al 2016

One thought on “Episode 15 MRSA: Make Resistance Susceptible Again

  1. OMG I loves this episode.
    I had MRSA on my face that for a long time the doctor tried to tell me was acne. It was a horrible bloody mess. Finally the doctor tested it and gave me some powerful antibiotics…which gave me the best complexion of my life.
    Anyways, this episode really helped to clear up questions I’ve always had about this gross episode in my life.

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